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Interestingly, a recent paper showed that inhibition of glucose metabolism leads to a reduction of ASCT2 glycosylation (see section Protein-protein Interactions, PTM and Structure/Function Relationships) in agreement with a refined concerted regulation of the two metabolic pathways (Polet et al., 2016)

At this point, it is unclear what the consequences of this local ROS accumulation at the ER-mitochondria MCS are, but ryanodine receptors 119 , IP 3 Rs and SERCA Ca 2+ pumps are known targets of ROS, which alter their activity 120

Branched-chain amino acids have been proven to increase muscle growth, prevent muscle wasting, and reduce exercise fatigue

Phys Biol 18:011002 Mlynarczuk-Bialy I, Dziuba I, Sarnecka A et al (2020) Entosis: from cell biology to clinical cancer pathology