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Cells were FBS starved for 6 hours with DMEM containing 0.1% BSA and incubated with KRH buffer (4 mM KH 2 PO 4 , 1 mM MgSO 4 , 1 mM CaCl 2 , 120 mM NaCl, 10 mM NaHCO 3 , 30 mM HEPES, pH 7.4) for 20 minutes

237 In proliferating cancer cells, one-carbon metabolism represents the second-largest intracellular NADPH source after the pentose phosphate pathway, with tetrahydrofolate oxidation generating substantial amounts of NADPH

Helps brighten the skin naturally and supports visible whitening Reduces pigmentation, dark patches and uneven tone Enhances glow and improves overall skin clarity Supports internal detoxification and provides strong antioxidant protection Minimizes dullness and promotes a clean, even looking complexion Helps maintain hydration and supports long term skin health and smoothness End of content End of content