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Some signs that may be present which are indicative of magnesium toxicity are hypotension, nausea and vomiting, diarrhea, facial flushing, retention of urine, ileus, respiratory depression and paralysis, loss of deep tendon reflexes, muscle weakness, sinoatrial (SA) or atrioventricular (AV) node blocks , and cardiac arrest

Furthermore, the suppression of invasion and metastasis in HCC by baicalein is strictly dependent on the hydroxyl substitution of its A-ring (C7) (Chiu et al., 2011)