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Cellular metabolites and drug byproducts often complicate chemotherapy efficacy with poorly defined molecular mechanisms 20,21,22,23

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Their low bioavailability, short half-life in the body, and complex metabolic conversion make it difficult to achieve effective therapeutic concentrations ( in vivo even when concentrations are extremely low, facilitating a more precise evaluation of their bioavailability ( Current reviews mainly focus on the impacts of particular subclasses of flavonoids or their effects within particular disease contexts, while a holistic perspective is absent

Oral supplements are valuable and Dr

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