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This glucose hypometabolism can potentially be countered by providing a dietary source of substrate to increase serum ketone bodies (23, 24) with, in the case of MCI, a direct and significant benefit in several cognitive domains (25)

That is worth knowing, because many L-carnitine supplements are sold in doses of 500 to 1,000 mg, which according to the meta-analysis may be below the optimal level

Feb 21 2023;12(3)doi:10.3390/antiox12030545

Finally, a 2007 review of the literature highlighted that plasma coenzyme Q 10 concentrations higher than normal were likely needed to promote coenzyme Q 10 uptake by peripheral tissues and different tissues may indeed require different plasma thresholds for the uptake of coenzyme Q 10 (102)

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