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Vitamin E (800 IU daily) has some evidence supporting its use in non-diabetic adults with biopsy-proven NASH, but this is specialist-initiated, off-label use requiring discussion of potential risks, including increased risk of haemorrhagic stroke and prostate cancer with long-term use

Doshis note: There is no single best form of glutathione for everyone

Multiple meta-analyses have found that smokers have significantly lower sperm count, poorer motility, greater morphological abnormalities, and higher rates of DNA fragmentation compared to non-smokers

These findings suggest that COs, especially those with CBD:THC ratios of 1:1 and 2:1 and terpenes, may represent a promising therapeutic approach for managing NAFLD and preventing its progression to more severe liver disease