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This research was funded by FORMULAMI Project, Funder: Ministero dello Sviluppo Economico, Number: F/310110/04/X56

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The rationale for using multiple chelators is so the individual dose of each agent can be lower, which reduces the risk of adverse events without decreasing clinical efficacy (Grady 2012)

However, further research is needed to understand the specific effects of KO on the skin under environmental stress and its potential to improve skin condition, as well as to elucidate the molecular mechanisms underlying the multiple benefits of KO on skin health

Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor