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The hydrophobic pocket is composed of residues Q247, E248, F249, A250, I258, Y273, G274, and Q302 of SEQ ID NO:2

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In a randomized, double-blind, placebo-controlled trial, 150 participants with ASD were assigned either an oral placebo, a whole plant cannabis extract containing CBD and THC at 20:1 ratio, or pure CBD and pure THC at the same ratio and concentration for a 12 week period

Subsequent morphological and histopathological evaluations of the rabbits aimed to assess the extent of cartilage degeneration post-exposure