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NAD + metabolism: pathophysiologic mechanisms and therapeutic potential

So, as the surrounding areas of your skin darken, it may have the effect of accentuating your stretch marks rather than diminishing their appearance

As expected, endo-IWR1, a specific inhibitor of canonical Wnt/-catenin signaling by increasing degradation of -catenin 25,26 , substantially reduced the expression of -catenin in a dose-dependent manner (Supplementary Figure 4a)