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Clear regulatory guidelines and early engagement with agencies are also being pursued to ensure that promising ferroptosis-based CVD therapies can enter clinical trials and, ultimately, patient care

In order to test a possible effect of intracellular glutathione synthesis in such a process, buthionine sulfoximine (BSO), a specific the inhibitor of gamma-glutamylcysteine synthetase, was used to block the first step of intracellular glutathione synthesis

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Sheridan et al., 2011

Consuming dried mushrooms even in small amounts (1015g rehydrated serving) delivers far more ergothioneine than any other dietary strategy