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Insulin resistance and oxidative marker in women with PCOS

10.1038/s41392-022-00955-7 109 KoumallosN.SigalaE.MilasT.BaikoussisN

Future research should employ subtype-specific models and single-cell multi-omics to map molecular signatures, clarify how driver mutations shape pathway heterogeneity and validate these insights for targeted therapy development

Furthermore, ROS contribute to the apoptotic pathway mediated by Trx-ASK1 and p38 in microglia, as Trx is an oxidative stress-sensitive marker that can trigger this pathway to regulate cell death (Noguchi et al., 2008

Numerous epidemiological studies have shown that a high intake of plant-based foods is associated with a lower risk of chronic disease and mortality [14,15,16]