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For example, the amplification of Myc causes cellular addiction to glutamine, which may be related to the combined effects of Myc and glutamine transporter (such as SLC7A5 and SLC1A5) promoter elements, leading to enhanced glutamine uptake, which induces the activation of Lactate Dehydrogenase A (LDHA) and transports glucose-derived citrate out of the mitochondria, thereby increasing the requirement of glutamine [29,30,31]

Discrepancies among clinical trials evaluating vasospasm treatments following aSAH largely stem from methodological heterogeneity, including underpowered and single-center designs, diverse patient populations, and inconsistent control of confounding factors

Chen J, Zhu H, Chen Q, Yang Y, Chen M, Huang J, et al

Warunki przechowywania Przechowywa w suchych pomieszczeniach, w temperaturze pokojowej, w szczelnie zamknitych opakowaniach

At the end of experiments, the rats were anaesthetised by isoflurane and euthanised by exsanguination