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According to a study on the metabolic effects of AOD 9604 in obese Zucker rats, the therapy significantly reduced body weight increase in comparison to the control group by more than 50%

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Interestingly, SFN-GSH was the 3rd most abundant metabolite detected in this study (after phosphorylcholine and PC(34:1)) based on LC-MS peak height, while SFN adducts with other peptides and amino acids were detected a low levels (Fig 7A and B)