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Expert Rev Mol Diagn (2015) 15(6):73547

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This increases the expression of miR-138-5p, which targets NLRP3 to inhibit pyroptosis [45] (Fig

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Pharmacokinetic and pharmacodynamic properties of cemdisiran, an RNAi therapeutic targeting complement component 5, in healthy subjects and patients with paroxysmal nocturnal hemoglobinuria