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Loss of sex and age-driven differences in the gut microbiome characterize arthritis-susceptible 0401 mice but not arthritis-resistant 0402 mice

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This is the first study to identify HO-1 deficiency in humans, exhibiting an increased inflammatory response

Other common viral, bacterial and protozoal agents were not identified because either they were not targeted by molecular assays in this screening, or detection may have been limited by sample type, assay sensitivity, or intermittent shedding

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