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In the Phase 2 Lancet trial, orforglipron 45 mg reduced HbA1c by up to 2.1 percentage points at 26 weeks, exceeding the reduction achieved by dulaglutide 1.5 mg (the active comparator)

Specifications: Form: Lyophilised powder Unit Size: 10 mg Appearance: White to off-white solid Storage (unreconstituted): -20 C, dark, dry Reconstitution: Sterile bacteriostatic water Stability (reconstituted): Store at 28 C, short-term Usage Notice: For research use only

Metabolites were identified and quantified using liquid chromatographymass spectrometry (LC-MS)

Human growth hormone fragment 176-191 and fat metabolism research

It is less preferred but used when there is less chance of absorption through skin