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Oxidative stress was one of the contributors in PD

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It was documented that IGF-I attenuated spontaneous apoptosis in these populations[175]

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Most importantly, most Nrf2 activators discussed in our review have multiple functions and molecular targets, therefore, pharmacological research still cannot completely replace the genetic approach

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To reinforce the value of PathoPlex as a foundational tool to perform unsupervised disease phenotyping, we used UnPaSt 42 to conduct label-free biclustering based on cluster abundances

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