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To speed up the process, combine topical treatments with lasers and chemical peels under medical supervision

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Provide reminders for follow-up injections or booster doses

reported a case series where nine of 33 patients (27%) had no response to V-B12.11 In this particular series, V-B12 was administered to patients who often had not met full criteria for vasoplegia syndrome but were provided V-B12 prophylactically or presumptively (e.g., in response to the surgeons requests), which may account for some limited responses