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We also showed that circulating T cells in AD are skewed towards a T H 2 profile and that HLA-DR, an activation marker, is significantly reduced in CD4 + T cells

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A27040, Invitrogen) and the samples were incubated at room temperature for 45 min in the dark

Other investigational compounds like acamprosate, neramexane, and AM-101 have also shown promise in clinical trials, though none are yet approved, highlighting the ongoing research need (Che et al., 2025)

Limit alcohol consumption, which may blunt response or worsen nausea