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The Stockwell group identified a novel small molecule, erastin, through a high-throughput screen for synthetic lethal compounds in 2003, which induced a nonapoptotic form of cell death [17]

bei viralen Infektionen, AIDS, Malignomen, Xenobiotika/-Schwermetallbelastung, Arteriosklerose (Lipidperoxide, erkennbar am erhhten MDA-LDL!), einigen Autoimmunerkrankungen (SLE, Rheumatoide Arthritis) sowie neurodegenerativen Erkrankungen

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The timeline typically looks like this: within the first 5-15 minutes, you'll notice initial hydration and electrolyte balance improvements