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For protein quantitation, reverse and contaminant proteins were removed

Moreover, in rat brain slices both GABA and glutamate uptake and release rates show very rapid and pronounced quantitative fluctuations during early development (Schousboe et al., Metabolism of GABA along the pathway suggested in Figure 7 would eliminate a need for uptake of exogenous aspartate and its conversion to malate in astrocytes in an aspartate-dependent pathway model for GABA formation suggested by LaNoue et al

The formation of NFT in an aerobic intracellular environment raises the question of its stability and its interaction with biological molecules such as the omnipresent glutathione

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[PubMed: 15161945] (Among 107 patients with atrial fibrillation or flutter treated with dofetilide in clinical practice, none developed torsades de pointes although 26% had excessive QTc prolongation, and rates of conversion to and maintenance of normal sinus rhythm were similar or higher than reported in registration trials