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[14] A dose of 200 mcg per day has been found to reduce TPO antibodies by about 50 percent within three months

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One challenge with defining the link between melanotan II and skin cancer is that the people developing cancer also have a history of high UV radiation exposure such as being regular tanning bed users

Other relevant interactions: Colchicine (used for gout) may affect B12 absorption with long-term use Chloramphenicol (rarely used antibiotic) may blunt the haematological response to B12 treatment Monitoring considerations: Patients taking loop or thiazide diuretics require careful monitoring when initiating B12 therapy in severe deficiency, due to the risk of hypokalaemia during rapid cell production