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The first drug in the class to be widely commercialized was dicoumarol itself, patented in 1941 and later used as a pharmaceutical

The 29-fold increase of CDNB activity observed in GSTP1 -transfected cells unambiguously demonstrated the over-expression of functional GSTP1

Aging (Albany NY) 11(21):92649279

Then, 3 days after the first dosing, the rats were exposed to a two-bottle taste preference test, that is, a voluntary choice between tap-water or the 0.1% saccharin solution