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The clinical evidence for NAD+ nasal spray specifically is still developing, even though the underlying NAD+ biology is well-established

When it comes to supplements, taking high doses of vitamin C at the same time as your B12 shot might slightly lower the amount of B12 your body can use, but this is more relevant for oral B12 supplements than injections

The guidance for neurological symptoms, recommending every-other-day injections, further highlights that the standard maintenance dose is not universally sufficient

(Folate deficiency disrupts normal DNA synthesis and methylation, which interferes with cell division and development, especially in rapidly dividing embryos.) Megaloblastic anemia, which can lead to symptoms like fatigue, weakness, and difficulty concentrating Elevated homocysteine, even when B12 levels are normal