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Arthritis Res Ther (2010) 12(4):R133

Case report: Osteolytic metastases from a pheochromocytoma presenting as multiple limb lameness and joint swelling in a dog

By eliminating oxidatively damaged DNA, autophagy maintains the metabolic balance and protects the genomic integrity of hematopoietic stem cells, preventing their malignant transformation under normal conditions (35,36)

Researchers continue to investigate how the combined biological activities represented in KLOW influence collagen biology, connective tissue maintenance, epithelial integrity, angiogenesis, and the complex signaling pathways involved in normal tissue homeostasis