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Sewell does a good job of separating what is established from what is speculative

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Progress and perspectives on targeting nanoparticles for brain drug delivery

This represents a novel antioxidant mechanism distinct from enzymatic antioxidantsit operates at the membrane level where ROS are generated

Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4