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What Evidence Would Be Needed

References: Auf der Heide E (2007): Agency for Toxic Substances and Disease Registry Case Studies in Environmental Medicine - Cholinesterase Inhibitors: Including Pesticides and Chemical Warfare Nerve Agents

9 Even amounts that exceed the recommended daily intake of 2.4 micrograms are not typically considered toxic because excess vitamin B12 is usually excreted through urine

In most cases, the burning went away by the second or third use

Soil quality is declining due to intensive farming practices Early humans received plenty of B12 from the good quality (cobalt-rich) soil that was yet to be intensively farmed and drained of nutrients, and because they drank dirty ("natural") water from rivers which also contained B12 and B12 producing bacteria