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Patient serum samples and outcomes data Pretreatment (pre-surgery and pre-chemotherapy) blood was collected from patients with newly diagnosed epithelial ovarian cancer under University of Pittsburgh approved IRB protocols 20050019, 19070449 and 19060197

The actual mechanism is likely to occur via two sequential steps with semiquinone (SQ . ) and superoxide (O2 . ) intermediates

PubMed: 17921186

Statins, besides lowering lipids, can inhibit RANKL expression and inhibit osteoclast precursor differentiation, suggesting potential value for bone protection in RA (185)