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Despite these constraints, innovations in genetic engineering and immunocompromised humanized mice can bring preclinical studies closer to clinical reality

Abstract Traumatic brain injury (TBI) is one of the most harmful forms of acute brain injury and predicted to be one of the three major neurological diseases that cause neurological disabilities by 2030

For bacteria, iron is also a co-factor in iron-containing proteins in redox reactions, metabolic pathways, and electron transport chain mechanisms (77)

Conversely, evaporative dry eye is predominantly attributed to elevated evaporation of the tear film, sometimes linked to meibomian gland dysfunction [63, 64]

The biogenesis of LDs under starvation is mediated by autophagy degradation of membrane organelles, and DGAT1 is required as an adaptive cytoprotective mechanism against lipotoxicity (Li et al., 2017)