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Injectable peptide therapy has a higher incidence of injection-site reactions (redness, swelling, mild itching), which is standard for subcutaneous injections and not specific to peptide therapy

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It mimics ghrelin signaling at the pituitary, triggering sustained growth hormone release

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Ultrapure water (18.2 M cm resistivity, Arium Comfort H2O-I-1-UV-T from Sartorius, Goettingen, Germany) or LC-MS grade water (LiChrosolv, Merck KGaA) was used throughout