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Graphical Abstract Highlights 1 Arsenic exposure reduced feed intake, super oxide dismutase, catalase, and glutathione peroxidase activities and growth in young goats

it is especially true for autoimmune connective tissue diseases (e.g., SLE), where some off-label therapies (e.g., rituximab) seem to work in selected cases in the everyday clinical routine but failed to show significant differences over placebo in clinical trials ( Despite the fact that there are many differences in the pathogenesis of systemic autoimmune diseases, many aspects are similar, leading to common molecular targets, like type I IFN/IFN receptor, IL-17, GM-CSF receptor, BAFF, CD40/40L, or JAK/STAT ( Table 2 )

Endogenous microRNAs (miRNAs/miRs) are a perennial research hotspot in the field of fibrotic disorders because of their involvement in regulating the Smad3-mediated TGF-/Smads pathway

Reactive oxygen species (ROS) are compounds that can build up in your cells over time and cause damage (known as oxidative stress) when they reach high enough levels

A common treatment for depression is the use of antidepressants