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From a biochemical standpoint, we're looking for favorable changes in those NAD+ levels and corresponding improvements in markers like fasting glucose and insulin sensitivity

Some studies have shown that metformin can reduce the absorption of vitamin B12 in 30% of people with type 2 diabetes (Vitamin B12 deficiency in metformin-treated type-2 diabetes patients, prevalence and association with peripheral neuropathy)

This can help you stay hydrated and prevent overconsumption

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Many patients begin to notice improvements in energy and body composition within a few weeks of starting therapy