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First, any transient gastrointestinal effects from the injection tend to be most noticeable in the first 24-48 hours, and experiencing them during the workweek means they typically resolve before the weekend

They may influence muscle signaling, appetite, or growth hormone stimulation, but their value for routine wellness care is limited by safety, regulatory, and evidence concerns

Ideally, blood tests (including full blood count, serum B12, folate, and possibly anti-intrinsic factor antibodies if pernicious anaemia is suspected) should be performed before starting supplements, as supplementation can affect test results

Your body stores B12 primarily in the liver, but continuous absorption through the stomach lining is necessary to maintain healthy levels

You can get a B12 shot as often as every week for best results