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The primary distinguishing factor is AOD 9604s structural modification for extended half-life and its more extensive research history, including human safety data

On the other hand, another study found that 3-month treatment with NR in a PD mouse model resulted in increased NMN and NAD + metabolism marker NAAD but did not increase NAD + levels 287

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Research in mice given 5-amino-1MQ showed a 7% reduction in body mass over 10 days without any changes in food intake, compared to controls