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Nevertheless, ALS is considered a multifactorial disease, due to a combination of risk-genotypes that interact with environmental factors, impacting and accelerating the neurodegenerative cascade ( Although numerous preclinical and clinical trials have been performed, a cure for ALS does not exist yet

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Compromised Autophagy & Mitophagy Autophagy or cellular detox and renewal, as well as mitophagy (a specific form of autophagy), regulates the renewal of cells and their mitochondria that are damaged or otherwise dysfunctional

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