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Levels remained significantly lower in this group after booster vaccines, given when the babies were 12 to 15 months old

This effect was likely due to ASTs ability to cross the BBB, scavenge free radicals, and alleviate FPN-induced oxidative stress 17

Intracellular targeting of peroxiredoxin 6 to lysosomal organelles requires MAPK activity and binding to 14-3-3$$

Therefore, targeting of the (pro)drugs and nanocarriers via transporters to the brain and release of the parent drug from the prodrug and nanocarriers at their site of action is desirable, although difficult to achieve in practice