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In autoimmune conditions, curcumin (1025 M) ameliorates disease severity by suppressing pathogenic Th1/Th17 responses while enhancing the activity of regulatory T cells (Tregs) ( + T-cell function and inactivating the AKT/mTORC1/STAT3/PD-L1 axis ( + T-cell differentiation into CD4 + CD25+FOXP3+ Tregs (Figure 2)

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I will postpone the 2nd dose in order to prevent further damage as I feel confident that the 1 dose is sufficient protection for now