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(PubMed) Laird E, O'Halloran AM, Molloy AM, et al

Cu,Zn-SODs, antioxidant enzymes, are linked to a number of diseases because they are essential for detoxifying ROS (Figure 5).The most common pathological conditions such as inflammatory bowel disease, obesity and its consequencesdiabetes and hypertensionand chronic obstructive pulmonary disease, have been linked to changes in Cu,Zn-SOD (SOD1 and SOD3) activity and its expression

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followed by 15 cycles each with denaturation step at 94 C for 30 s, annealing at 55 C and extension at 72 C for 5 min

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