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Lontoforesis (corriente galvnica)

Chemotherapy-induced peripheral neuropathy (CIPN) is a common, dose-limiting adverse drug reaction in cancer treatment (1), which primarily presents as varying degrees of motor and sensory deficits, as well as autonomic dysfunction

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Therefore, it can form a variety of stable chelates with many metal ions, such as copper, zinc, manganese [2], magnesium, calcium, etc

Materials and methods Experimental design Thirty-six experimentally nave rats, male, Wistar strain, 3-4 months old, weighing 193 12 g at the beginning of the experiment, were used as subjects