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Some clinically approved AEDs, such as Perampanel and Valproate, target these two receptors on the postsynaptic neuron to control the generation or propagation of the action potential in epilepsy (Tomson et al., 2023)

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Rather than targeting obesity through a single mechanism, this 3-way agonist addresses the complex hormonal and metabolic networks that regulate body weight, treating obesity as the multifaceted metabolic disease it truly is

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