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2000;59(suppl 1):i6571

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166 ASK1 activity, protein levels, and phosphorylation were increased in PAFs of IPAH patients, and ASK1 promoted pathological remodeling of pulmonary vessels and right ventricle in rat MCT- and Su/Hx-PAH models

The increase in prostate volume causes bladder obstruction and physical compression of the urethra leading to discomfort clinically referred to as lower urinary tract symptoms (LUTS) [1, 2]