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doi: 10.3390/cells11233756 40 NsiahN

In contrast, NOX 4 plays important roles in endogenous detoxification reactions, angiogenesis, ERS, substrate utilization, and stress responses (40)

In cellular models, GSH depletion increases neuronal death in striatal neurons expressing mHTT, reinforcing the role of GSH-dependent redox imbalance in HD progression (400)