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Some studies have shown that ion channels (such as ATP-dependent K + channels and Ca 2+ -activated K + channels) play a role in adapting to changes in the high-altitude hypoxic environment by altering serum ion levels

A dietary intervention with reduction of starch and sucrose leads to reduced gastrointestinal and extra-intestinal symptoms in IBS patients

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[38] [36] -KIC is mostly metabolized by the mitochondrial enzyme branched-chain -ketoacid dehydrogenase, which converts it to isovaleryl-CoA

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