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Furthermore, previous studies indicate that charged residues adjacent to aggregation-prone regions act as gatekeepers to prevent aggregation 41

Bibcode:2014FrPS....5..442G

Another translational initiation site is found in exon 1b

Experimental mouse groups were treated with the caspase1 inhibitor AcYVADcmk (25 g/mouse caspase1 inhibitor II in DMSO, Calbiochem) subcutaneously daily from the day of the laser treatment