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In a cancer setting, M1 macrophages generally promote inflammation and active antitumor immune responses

J Proteome Sci

[103] [100] [104] Several other applications to sell generic versions have been made, but not yet approved, including by Aspen Pharmacare, Sandoz, Taro Pharmaceuticals and Teva Pharmaceuticals

doi: 10.1016/j.ccell.2016.04.002 57 ShangSHuaFHuZW

Evaluation of other naphthoquinones and juglone analogues against ChaC1 reveals plumbagin as a second inhibitor against ChaC1 The MD simulations suggested that the Juglone-GS conjugate formation was responsible for the inhibition of ChaC1 (and not juglone per se ) since other known mechanisms were eliminated