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Abstract Organoids have emerged as revolutionary biomimetic systems that offer a physiologically relevant in vitro model to study the specific tissue or organ of origin

doi:10.1038/s41591-024-02970-5 PubMed: This substudy demonstrated that retatrutide reduced liver fat by 81-82% at the 8mg and 12mg doses over 24 weeks, providing evidence of retatrutides multi-system metabolic benefits beyond weight loss

Air pollution and Parkinson's disease evidence and future directions

417 Notably, cytokine-based intervention with IL-4 administration confers cytoprotective effects on macrophages while enhancing their survival capacity, ultimately ameliorating age-associated physiological decline and increasing health span parameters in geriatric mouse cohorts

GSH has the function of master antioxidant in all tissues and is involved in antioxidant defense, detoxication of xenobiotics, intracellular redox homeostasis, cysteine carrier/storage, cell signaling, protein folding and function, gene expression, cell differentiation/proliferation, immune response and antiviral defense, that make it a Samsonian (mighty) little molecule (1, 2)