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B., Malagrino, F., Arese, M., Forte, E., Sarti, P

29,30 Interestingly, cell death induced by these RSLs did not involve classical features of apoptosis but seemed to depend on reactive oxygen species and iron

It is crucial for reducing oxidative stress, sustaining redox balance, supporting metabolic detoxification, and modulating the immune system [16]

The THP-1 cells were seeded in 6-well plates and the culture supernatants were collected after 24 h normoxia or hypoxia intervention

Therapy with a GLP-1 RA or sodium-glucose cotransporter 2 inhibitor (SGLT2 inhibitor) that has proven CV benefit is recommended for initial therapy, with or without metformin based on glycemic needs, in patients with indicators of high-risk or established CV disease