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IL-1 and IL-6 also induce changes in the TJs [79, 80]

Lastly, although the following genes are implicated in AD at late stages, we did not find differences between Wt and Tg expression of Ape1 137,138 , Cdk5 137,139,140,141,142,143 , Parp1 105 , Pcna 144,145 , Pol 146,147 , or Sirt3 148,149,150 ,

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Also, in some cases, ME/CFS is triggered by non-viral factors, such as emotional stress, major life events and physical trauma, which is not the case for long COVID [5]