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"I felt like a drug addict begging for a fix because that was how they treated me." Hope is on the horizon The updated NICE guidelines recommend that GPs consider the possibility of vitamin B12 deficiency in patients exhibiting one symptom or one risk factor

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In part, Georges case was able to be successfully managed because his primary care vet had realised what his lump might be, and not tried to remove it

Therapeutic efforts now focus on mitigating mitochondrial dysfunction through the use of antioxidants, enhancing mitophagy, modulating mitochondrial dynamics, and improving inter-organelle communication [Table 1]