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An alternative approach is to remove the erythrocytes from whole blood first by aggregation with dextran [2-4], methylcellulose [5,6] hetastarch [7] or Plasmagel [8,9] and then layer the resulting leukocyte-rich plasma (LRP) over the Nycoprep 1.077A, so that the PMN pellet contains only a very small percentage of residual erythrocytes

10.2147/ijn.S146978 93 TuH.MaD.LuoY.TangS.LiY.ChenG.et al (2021)

Wang Y, Lin Q, Zhang H, Wang S, Cui J, Hu Y, et al

Heitzer T, Wenzel U, Hink U, Krollner D, Skatchkov M, Stahl RA, MacHarzina R, Brasen JH, Meinertz T, Munzel T

Depending on the ingredients, it can address various skin concerns such as dark spots, acne, and excess oil